diffuse large b cell lymphoma survival rate | CHILDHOOD CANCERS: LYMPHOMA

CHILDHOOD CANCERS: LYMPHOMA



Lymphomas are cancers of the system nodes in children under 15 years, the most common lymphomas is a "non-Hodgkiniens". " In adolescents and adults, this is rather of Hodgkin lymphoma.
Features
Lymphomas develop at the expense of the white blood cells or lymphocytes, which help the body to fight infections.

In children, 4 subtypes of type "non-Hodgkiniens Lymphoma" (NHL) can be diagnosed: Burkitt Lymphoma (B-cell), Lymphoblastic Lymphoma (at T or pre - B cells), anaplastic large cell lymphoma and diffuse B Lymphoma " large cell.

The LHN occur in the lymph nodes distributed throughout the body or at the level of this lymphoid tissue in many organs. They can occur in several parts of the body.

Only a biopsy can confirm the diagnosis of a NHS and determine its subtype. The diagnosis can be done by a cytological puncture, but still sometimes requires surgical resection of Lymphadenopathy, for example.

Treatment relies almost exclusively on a combination chemotherapy (association of several chimoitherapies).

Tumors that respond to current treatments
The NHL are very sensitive to chemotherapy, major therapeutic tool. Radiotherapy is used for exceptional guidance.

The treatment is based on a poly-chimiotherapie adapted to the type of lymphoma. The duration and intensity of treatment vary also depending on the type of lymphoma, and varies from 2 months (for localized and made completely of Burkitt lymphomas) to 2 years for all lymphomas.

Targeted Therapeutics, most frequently monoclonal antibodies, make their appearance. The aim of these treatments is to maintain and improve the very good cure rate, while reducing the harmful effects of chemotherapy.

Key figures
Lymphomas "non-Hodgkiniens" (NHL) occur at all ages of childhood but are exceptional before 2 years and appear more boys "
A good prognosis with a greater than 70% overall 5-year survival
Nearly 200 cases of lymphomas diagnosed in less than 15 years, every year in France.