diffuse large b cell lymphoma symptoms | Lymphoma

 Lymphoma




Brief description of the disease
Lymphoma - a malignant disease of the lymphatic system of the person. Lymphoma is characterized by tumors in the lymph system or internal organs.

The symptoms of lymphoma
Typically, an early symptom of lymphoma is an increase in the size of the lymph nodes in the armpits, groin or neck level. Dimensions nodes will not fade over time and do not respond to treatment with antibiotics. The lymph nodes do not cause pain. If you increase the internal organs (liver, spleen) can be observed in the distension of the abdomen, breathing problems, pain in the lower part of the back.

In addition, the symptoms of lymphoma is a weakness, perspiration, a high fever, exposure to infectious diseases, disorders digestive problems, weight loss.

Types of lymphoma
There are two groups of tumors: the Hodgkin lymphoma and nehodzhinskie.

Hodgkin's lymphoma is characterized by the presence of a type of cell in the body, also known known as Reed-Sternberg cell. Define these cells may be exploring the lymphoid tissue under a microscope. The treatment of Hodgkin's disease is different from the treatment of lymphomas nehodzhinskih, so that proper diagnosis is important.

Hodgkin's lymphoma is more common in young age. So far not revealed the exact cause of the disease.

The risk factors for Hodgkin's disease is a low immunity, infection by the Epstein-Barr virus, which causes Infectious Mononucleosis.

The main symptom of Hodgkin's disease is the lymph nodes from the groin, the neck and armpits. In addition, a high fever, night sweats, cough, weight loss, itching, fatigue.

Lymphoma Nehodzhinskie
Lymphoma Nehodzhinskie includes a fairly large group of lymphomas. They have subtypes, which are different evolution and prognosis of diseases.

Indolent lymphomas are characterized by a long history and a good prognosis. These types of tumors require no treatment, but require constant monitoring by a doctor.

Aggressive lymphomas - the exact opposite of lazy. This type of cancer needs immediate treatment because of the rapid progression of symptoms and the progression.

Extranodal lymphoma characterized by the development of the disease to do not the lymph nodes and internal organs: intestine, spleen, lung, stomach, brain.

30 40% of all lymphomas diffuse large B-cell lymphoma nehodzhinskih. Large cell lymphoma often suffer from elderly, but can get sick and children. The main symptom of lymphoma large cell is a rapid increase in the tumor. Diffuse large cell lymphoma refers to one of the aggressive forms of lymphoma, and requires immediate treatment.

The classification of lymphomas

The classification of lymphomas is quite broad and includes many types. All lymphomas can be divided according to these factors:

-Appearance;

-Mutation;

-The grouping of cells, lymphomas form clusters - groups of cells, others are scattered node or organs of the body lymph;

-The type of cells, causing the tumor;

-Type of protein on the surface of lymphoma cells;

-What did the body beat lymphoma.

Stage Lymphoma

There are four stages of lymphoma.

The first stage is characterized by lesions of lymph nodes of the same area.

The second stage is characterized by lesions of two or more areas on one side of the membrane.

The third stage is characterized by lesions of the lymph nodes on both sides of the membrane.

The fourth stage is characterized by a generalization of the process.

The diagnosis of lymphoma

For the diagnosis of lymphoma using different methods. The main method of diagnosis of lymphoma is a biopsy. This method allows to determine the presence of tumor cells in the tissue.

In addition, using x-rays, CAT scan or MRI, which can not only detect the presence of a tumor, but also to determine the stage of lymphoma.

In addition, a bone marrow examination is performed to determine if bone lymphoma cells.

Treatment for lymphoma

 Aggressive lymphoma treatment aims to improve the well-being of the patient

  Lymphoma treatment depends on the stage, forms and symptoms. Form of indolent Lymphoma in the absence of symptoms and illness needs to be treated. But when the signs of growth are starting treatment of lymphoma. If the tumor has a local location, use radiation therapy. In more serious golf course of the disease and use extensive chemotherapy.

Treatment of aggressive lymphoma requires a rapid response to the situation. The most effective treatment for this type of lymphoma is considered several cycles of chemotherapy, and failure - a bone marrow or stem cell transplant. Among the drugs for the treatment of lymphoma, a prescribed form aggressive vincristine, cyclophosphamide, rituximab, hlorbutin and others. The main objective of the aggressive form of lymphoma treatment is to improve the well-being of the patient as a full recovery is unlikely.

Forecasts lymphomas

Hodgkin - good forecasts. Modern treatment lymphoma can get good results. Five years survival after treatment of Hodgkin's disease is 80-90%.

lymphomas forecasts nehodzhinskoy forms when time started treatment and the use of modern technology and medicine is about 55 percent for adults and 80% of children.