Overview of follicular Lymphoma
Follicular Lymphoma (FL) is a malignant disease of the lymphatic system of the body and a weaker form of non-Hodgkin lymphoma. (more info about the term of lymphomas No. hodgkiniens)
Frequency and causes
Follicular lymphomas constitute about 25% of all cases of NHL and so are the most common (second most in Europe, in the most common North American) forms of malignant lymphomas. Compared to other cancers, it is follicular Lymphoma, but a rare disease.
Symptoms
Early symptoms of follicular lymphoma are usually painless enlargement of lymph nodes. A FL property is that they cause no specific and sometimes very little complaints about less serious diseases. It's fatigue, loss of appetite, nausea or heartburn, as well as an increase in the susceptibility. In addition, common clinical symptoms occur in follicular Lymphoma, for example by an infiltration of bone marrow (bone marrow infection) with anemia resulting ("Blutarmut";") Disorder of the transport of oxygen in the blood), thrombocytopenia (decrease in the number of platelets) is due.
Ranking
"The term "follikulares Lymphoma "comes from the who classification and includes the classification of Kiel zentroblastisch/Centrocytic Lymphoma. "It's normal germ cells disease center of secondary follicles
Diagnosis
FL run quietly (indolent), usually over several years and are not always immediately be treated. Usually the diagnosis is done only at an advanced stage.
Therapy
The treatment of the FL is depends on the stage of the disease and the patient's physical condition. There are various treatment options available, which are often combined or be used at a time.
Complications & side effects
Side effects may be according to the form of treatment - nausea, vomiting, diarrhea, hair loss, bone marrow, Blutzellarmut lesions and infections. In addition, organ damage, and allergic reactions are possible. Two tumors have been described as a delayed effect.
Aftercare
Follow-up after the end of treatment is used to detect relapse or progression of the disease. In this case, a new treatment for follicular lymphoma is often necessary.
Group (GLSG) German study Niedrigmaligne lymphomas
The treatment of follicular lymphoma is developed mainly with clinical and improved therapy optimization studies. Therefore, all patients with LLC as part of these studies must be treated. The German study group Niedrigmaligne Lymphoma (GLSG) results in clinical studies in the field of follicular Lymphoma (level 1, 2 or 3 a).
Contact data of the GLSG study group
Centers of studies research
You will find treatment centers who participate in studies of KML study groups in the registry of the trial of KML in the respective studies.
The KML trial registry
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