b cell non hodgkin's lymphoma | What is Lymphoma non-Hodgkin in children?

What is Lymphoma non-Hodgkin in children?



No (NHL) Hodgkin lymphoma is a cancer that originates in lymphocytes. Lymphocytes are cells of the lymphatic system.

The lymphatic system acts in concert with other parts of your immune system to help your body fight infections and diseases. The lymphatic system consists of a network of lymph vessels, lymph nodes and lymphatic organs. The vessels carry lymph which contains lymphocytes and other white blood cells and antibodies and nutrients. Lymph nodes, which are located along the lymphatic vessels, their role is to filter the lymph. The lymphatic organs include the spleen, thymus, tonsils, the adenoids and bone marrow.

Lymphocytes develop in the bone marrow from cell precursors called stem cells. These can produce different types of cells that have different functions. Lymphocytes are a kind of white blood cells that help fight infections. There are 2 types, either:

B (B-cells) cells that remain in the bone marrow until they reach maturity;
T-cells (T-cells) that migrate to the thymus to continue their development.
Lymphocytes are sometimes undergoing changes that make their way of growth or abnormal behaviour. These abnormal cells may form tumors called lymphomas. No (NHL) Hodgkin lymphoma can start in the B lymphocytes or the T lymphocytes. The 4 main types of NHL in children include:

Burkitt Lymphoma, including type Lymphoma Burkitt
Lymphoblastic Lymphoma (usually called Lymphocytic Lymphoma in adults)
primitive diffuse large cell B, including mediastinal Lymphoma Lymphoma B-cell
anaplastic large cell lymphoma
Rare types of NHL may also manifest. Lymphoproliferatif syndrome post-transplant (SLPG) is a rare form of NHL, which may appear after a transplant of a full body. Follicular NHL and the marginal zone B-cell lymphoma are extremely rare in children.

Not all cells of different types of NHL have the same appearance under the microscope; In addition, they grow and spread in different ways. Most of the NHL in children are high grade due to their growth and their rapid evolution. The doctor will determine what type of lymphoma non Hodgkin your child is reached to ensure that he gets the most effective treatment in this case.

The NHL can occur in almost any part of the body of the child, because the lymphocytes are present everywhere in the lymphatic system. It usually appears in a group of lymph nodes in a given region, as the neck (above the collarbone), thorax, abdomen or groin. Sometimes, children also have the spleen, swollen at the time of diagnosis. The NHL in children does not predictably spread. It can spread to almost any tissue or organ of the body through the lymphatic system or blood.

The other main form of cancer of the lymphatic system that can affect children and adolescents is Lymphoma Hodgkin (LH). Abnormal B cells of Hodgkin lymphoma are appearance and a different behavior than the lymphoma cells no Hodgkin. These two categories of lymphomas are treated differently.