B-cell lymphoma: treatment Perspective, types and others
B-cell lymphoma: treatment Perspective, types and others
Overview
Lymphoma is a type of cancer that begins in lymphocyte. Lymphocytes are cells of the immune system. Hodgkin's and non-Hodgkin's lymphoma are the two main types of lymphoma.
T-cell lymphoma and B-cell lymphoma are two types of non-Hodgkin's lymphoma. There is also a rare type of lymphoma called NK cells.
Among people with non-Hodgkin's lymphoma, approximately 85% of B-cell lymphoma.
Treatment of B-cell lymphomas are based on specific subtype and stage of the disease.
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Subtypes
What are the subtypes B-cell lymphomas?
There are many subtypes of B-cell lymphoma, both slow growing (indolentă), and in the fast-growing (aggressive), including:
Subtype B cell Lymphoma with Features large B cell diffuse (DLBCL) this is the most common type of non-Hodgkin's lymphoma. It is an aggressive but treatable cancer, which may involve the lymph nodes and other organs. Follicular lymphoma: this is the second most common type in non-Hodgkin's lymphoma. It is slow growing and usually begins in the lymph nodes. Mantel cell lymphoma generally involves the lymph nodes, bone marrow, spleen and gastrointestinal system. Chronic lymphocytic leukemia (CLL)/limfocitar Lymphoma (SLL) this guy is indolență and normally affects the blood and bone marrow (CLL) or the lymph nodes and spleen (SLL). Primary Lymphoma of the central nervous system of this type usually starts in the brain or the spinal cord. It is associated with immune problems caused by AIDS or drugs used rejection after organ transplantation. B cell lymphoma from Lymphoma splenic lymphocytes area this is a type of slow growth that begins in the spleen and bone marrow. Lymphoma from Lymphoma of the MALT extranodală limit This type involves usually the stomach. May occur and in the lungs, skin, thyroid, salivary gland or in the eye. Lymphoma lymph lymphatic cells (B) It is a rare, slow-growing, which is found mostly in the lymph nodes. Burkitt's lymphoma: this is a type of rapid growth that is more common in children. Hairy cell leukemia this is a slow growing type that affect the spleen, lymph nodes and blood. Limfoplasmacytic Lymphoma (Waldenstrom macroglobulinemia) this is a rare Lymphoma, a slow increase in the bone marrow, spleen and lymph nodes. Primary effusion Lymphoma It is a rare, aggressive type that tends to occur in people who have a weakened immune system.
Staging
Cancer is conducted according to the extent to which it has spread from the original site. Non-Hodgkin's lymphoma is organized from 1 to 4, of which 4 are most advanced.
Symptoms
What are the symptoms?
Symptoms vary depending on the type of lymphoma of B cells and how advanced it is. These are some of the main symptoms:
become swollen lymph nodes in the neck, armpit or înghinență
abdominal pain or swelling
chest pain
cough
difficulties breathing
fever and night sweats
weight loss
fatigue
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Treatment
How is it treated?
Certain types of lymphoma that are asymptomatic and indolent does not necessarily require treatment. Your doctor. can you advise what is known as "staging vigilant". This means that you will watch a couple of months to make sure that the cancer progresses. In some cases, this may take years.
Treatment may begin when symptoms occur or if there are signs of progression of the disease. B-lymphoma cells often involve a combination of treatments, which may change over time.
Radiation
Using high-powered beams of energy, radiation therapy is used to kill cancer cells and reduce tumors. It takes a lot to sit on a table, while the beams are directed towards a precise point on your body.
For lymphoma with slow growing, localized, radiation therapy may be just what you need.
Side effects may include fatigue and skin irritation.
Chemotherapy
Chemotherapy is a systemic treatment that can be administered orally or intravenously. Some aggressive B-cell lymphoma can be cured with chemotherapy, particularly in early-stage disease.
DLBCL is a fast-growing type that can be treated with a regimen of chemotherapy called CHOP (cyclophosphamide, doxorubicin, vincristine and prednisone). When it is administered along with the monoclonal antibody rituximab (Rituxan) is called R-CHOP. It is usually given in cycles in several weeks. It's hard in the heart, so it's not an option if you have pre-existing heart problems.
The side effects of chemotherapy include nausea, fatigue and hair loss.
Immune therapy
Biological drugs helps the immune system to fight cancer. Rituximab proposes proteins on the surface of B cells, thereby facilitating the identification and destruction of the immune system. By decreasing the number of cancerous and healthy B cells, the drug requires the body to produce healthy new cells B. This makes it less likely that the cancer to recur.
Radiomunoterapie medicines, such as ibritumomab tiuxetan (Zevalin), monoclonal antibodies are manufactured from carrying radioactive isotopes. The drug helps to antibodies attach to cancer cells for direct release of radiation.
Side effects of immune therapy may include a decrease in the number of leukocytes, fatigue and infections.
Stem cell transplantation
A stem cell transplantation involves replacing the bone marrow with marrow from a healthy donor. First, you will need high-dose chemotherapy or radiation for suppressing the immune system to kill cancer cells and to make room for the new marrow. To be eligible, you must be healthy enough to resist this treatment.
Side effects can include infection, anemia, and rejecting the new bone marrow.
Complications
There are possible complications?
Weaken your immune system lymphomas, making you more vulnerable to infections. Some treatments for lymphoma can cause complications such as:
infertility
diseases of the heart, lungs, kidney and thyroid
Diabetes
the second case of cancer
B cell lymphoma can grow and can spread to distant organs.
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Recovery
What is recovery?
Some types of B-cell lymphoma can be cured. Treatment can slow the progression in others. If there are no signs of cancer after primary treatment, means that you are in remission. You still need to follow several years to monitor recurrence.
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Outlook
Outlook
Relative survival rate of five years for non-Hodgkin's lymphoma is 70%. This varies greatly depending on the type of lymphoma of B cells and stage at diagnosis. Other considerations are your age and general health.
For example, curabil DLBCL is in about half of the people who have it. Those who begin treatment in the previous stages have a better vision than those who have end-stage disease.
Your doctor can provide you with your forecast. based on your personal profile. full health.







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